ZIC3

Zic family member 3
OMIM: 300265, Gene2Phenotype

17 panels

Panel	Reviews	Mode of inheritance	Details
Filter panels 17 panels
Red ZIC3 in Arthrogryposis Level 2: Neurology and neurodevelopmental disorders Version 0.411 Component of the following Super Panels: Neuromuscular Superpanel	review	X-LINKED: hemizygous mutation in males, biallelic mutations in females	Sources Expert Review Red Victorian Clinical Genetics Services Phenotypes Heterotaxy, visceral, 1, X-linked, MIM# 306955 VACTERL association, X-linked, MIM# 314390
Green ZIC3 in Congenital anomalies of the kidney and urinary tract (CAKUT) Syndromic Level 2: Renal and urinary tract disorders Version 0.138 Component of the following Super Panels: Congenital abnormalities of the kidneys and urinary tract (CAKUT)_SuperPanel Kidneyome_SuperPanel	review	X-LINKED: hemizygous mutation in males, biallelic mutations in females	Sources Expert Review Green Expert list Phenotypes VACTERL association, X-linked, MIM#314390
Green ZIC3 in Congenital Heart Defect Level 2: Cardiovascular disorders Version 0.418	review	X-LINKED: hemizygous mutation in males, monoallelic mutations in females may cause disease (may be less severe, later onset than males)	Sources Expert Review Green Victorian Clinical Genetics Services Phenotypes Heterotaxy, visceral, 1, X-linked (MIM#306955)
Red ZIC3 in Ciliopathies Level 2: Dysmorphic and congenital abnormality syndromes Version 1.54	review	X-LINKED: hemizygous mutation in males, biallelic mutations in females	Sources Expert Review Red Victorian Clinical Genetics Services Phenotypes Heterotaxy, visceral, 1, X-linked (MIM#306955)
Green ZIC3 in Heterotaxy Level 2: Dysmorphic and congenital abnormality syndromes Version 1.32	review	X-LINKED: hemizygous mutation in males, monoallelic mutations in females may cause disease (may be less severe, later onset than males)	Sources Expert Review Green Expert Review Phenotypes Heterotaxy, visceral, 1, X-linked (MIM#306955)
Green ZIC3 in Hydrocephalus_Ventriculomegaly Level 2: Neurology and neurodevelopmental disorders Version 0.123	review	Unknown	Sources Victorian Clinical Genetics Services Expert Review Green
Green ZIC3 in Mendeliome Version 1.1891	review	X-LINKED: hemizygous mutation in males, biallelic mutations in females	Sources Expert Review Green Victorian Clinical Genetics Services Victorian Clinical Genetics Services Phenotypes Congenital heart defects, nonsyndromic, 1, X-linked (MIM#306955) Heterotaxy, visceral, 1, X-linked (MIM#306955) VACTERL association, X-linked, MIM# 314390
Green ZIC3 in Radial Ray Abnormalities Level 2: Dysmorphic and congenital abnormality syndromes Version 1.10 Component of the following Super Panels: Limb and Digital Malformations SuperPanel	review	X-LINKED: hemizygous mutation in males, biallelic mutations in females	Sources Expert Review Green Expert list Phenotypes VACTERL association, X-linked 314390
Green ZIC3 in Callosome Level 2: Neurology and neurodevelopmental disorders Version 0.522	review	Unknown	Sources Victorian Clinical Genetics Services Expert Review Green
Red ZIC3 in Skeletal dysplasia Level 3: Skeletal dysplasias Level 2: Skeletal disorders Version 0.285	review	Not set	Sources Expert Review Green Emory Genetics Laboratory Victorian Clinical Genetics Services Victorian Clinical Genetics Services
Green ZIC3 in Mackenzie's Mission_Reproductive Carrier Screening Level 2: Screening Version 0.109	review	X-LINKED: hemizygous mutation in males, biallelic mutations in females	Sources Expert Review Green Mackenzie's Mission Phenotypes Congenital heart defects, nonsyndromic, 1, X-linked, 306955 (3)
Green ZIC3 in Additional findings_Paediatric Level 2: Screening Version 0.278	review	X-LINKED: hemizygous mutation in males, biallelic mutations in females	Sources BabySeq Category A gene Expert Review Green Phenotypes Heterotaxy
Green ZIC3 in Clefting disorders Level 3: Dysmorphic disorders Level 2: Dysmorphic and congenital abnormality syndromes Version 0.252	review	X-LINKED: hemizygous mutation in males, biallelic mutations in females	Sources Expert Review Green Phenotypes VACTERL ASSOCIATION, X-LINKED, WITH OR WITHOUT HYDROCEPHALUS VACTERLX
Green ZIC3 in Fetal anomalies Version 1.255	review	X-LINKED: hemizygous mutation in males, biallelic mutations in females	Sources Expert Review Green Genomics England PanelApp Expert list Expert Review Phenotypes Congenital heart defects, nonsyndromic, 1, X-linked, MIM#306955 Heterotaxy, visceral, 1, X-linked, MIM#306955 VACTERL association, X-linked, MIM#314390
Green ZIC3 in Prepair 1000+ Level 2: Screening Version 1.9	review	X-LINKED: hemizygous mutation in males, biallelic mutations in females	Sources Expert Review Green Mackenzie's Mission Phenotypes Congenital heart defects, nonsyndromic, 1, X-linked, 306955 (3)
Red ZIC3 in BabyScreen+ newborn screening Level 2: Screening Version 1.113	review	X-LINKED: hemizygous mutation in males, biallelic mutations in females	Sources Expert Review Red BabySeq Category A gene Phenotypes X linked heterotaxy and congenital heart defects MIM:306955
Red VACTERLX STR in Repeat Disorders Version 0.167	review	X-LINKED: hemizygous mutation in males, biallelic mutations in females	Sources Expert Review Red Literature Phenotypes VACTERL association, X-linked MIM#314390 Tags paediatric-onset