IKZF1

IKAROS family zinc finger 1
OMIM: 603023, Gene2Phenotype

6 panels

Panel	Reviews	Mode of inheritance	Details
Filter panels 6 panels
Green IKZF1 in Mendeliome Version 1.1891	review	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Sources Expert Review Green Victorian Clinical Genetics Services Phenotypes Immunodeficiency, common variable, 13 MIM# 616873 recurrent bacterial respiratory infections Thrombocytopaenia immunodeficiency Hypogammaglobulinaemia decrease B-cells decrease B-cell differentiation decrease memory B/T cells Low Ig pneumocystis early CID onset Immune dysregulation
Green IKZF1 in Predominantly Antibody Deficiency Level 2: Immunological disorders Version 0.135 Component of the following Super Panels: Immunological disorders_SuperPanel	review	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Sources Expert Review Green Expert list Phenotypes Immunodeficiency, common variable, 13, MIM# 616873 Low IgG, IgA, IgM, low or normal B cells B cells and Ig levels reduce with age Decreased pro-B cells Recurrent sinopulmonary infections Increased risk of ALL, autoimmunity
Green IKZF1 in Combined Immunodeficiency Level 2: Immunological disorders Version 1.66 Component of the following Super Panels: Immunological disorders_SuperPanel	review	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Sources Expert Review Green Melbourne Genomics Health Alliance Immunology Flagship Victorian Clinical Genetics Services Phenotypes Immunodeficiency, common variable, 13 MIM# 616873 recurrent bacterial respiratory infections Thrombocytopaenia immunodeficiency Hypogammaglobulinaemia decrease B-cells decrease B-cell differentiation decrease memory B/T cells Low Ig pneumocystis early CID onset
Green IKZF1 in Common Variable Immunodeficiency Level 2: Immunological disorders Version 1.12 Component of the following Super Panels: Immunological disorders_SuperPanel	review	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Sources Expert Review Green Melbourne Genomics Health Alliance Immunology Flagship Victorian Clinical Genetics Services Phenotypes Immunodeficiency, common variable, 13 MIM# 616873 recurrent bacterial respiratory infections Thrombocytopaenia immunodeficiency Hypogammaglobulinaemia decrease B-cells decrease B-cell differentiation decrease memory B/T cells Low Ig pneumocystis early CID onset
Green IKZF1 in Disorders of immune dysregulation Level 2: Immunological disorders Version 0.186 Component of the following Super Panels: Immunological disorders_SuperPanel	review	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Sources Expert Review Green Literature Phenotypes Immune dysregulation
Green IKZF1 in BabyScreen+ newborn screening Level 2: Screening Version 1.113	review	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Sources Expert Review Green Expert list Phenotypes Immunodeficiency, common variable, 13 MIM# 616873 Tags treatable immunological