PanelApp (stage)
  1. Genes and Genomic Entities
  2. ADAMTS10

ADAMTS10

ADAM metallopeptidase with thrombospondin type 1 motif 10
OMIM: 608990, Gene2Phenotype

10 panels

Panel Reviews Mode of inheritance Details
10 panels

Green ADAMTS10 in Aortopathy_Connective Tissue Disorders


Level 2: Cardiovascular disorders
Version 1.85

review BIALLELIC, autosomal or pseudoautosomal
Sources
  • Expert Review Green
  • Other
Phenotypes
  • Weill-Marchesani syndrome 1, recessive MIM#277600

Green ADAMTS10 in Arthrogryposis


Level 2: Neurology and neurodevelopmental disorders
Version 0.411

Component of the following Super Panels:

  • Neuromuscular Superpanel

    		•  review Unknown
    Sources
    • Expert Review Green
    • Expert list
    • Victorian Clinical Genetics Services
    Phenotypes
    • Weill-Marchesani syndrome 1, recessive, MIM#277600

    Green ADAMTS10 in Cataract


    Level 2: Ophthalmological disorders
    Version 0.366

    		review Unknown
    Sources
    • Victorian Clinical Genetics Services
    • Expert Review Green

    Green ADAMTS10 in Congenital Heart Defect


    Level 2: Cardiovascular disorders
    Version 0.418

    		review BIALLELIC, autosomal or pseudoautosomal
    Sources
    • Expert Review Green
    • Victorian Clinical Genetics Services
    Phenotypes
    • Weill-Marchesani syndrome 1, recessive, MIM# 277600

    Green ADAMTS10 in Glaucoma congenital


    Level 2: Ophthalmological disorders
    Version 1.9

    		review BIALLELIC, autosomal or pseudoautosomal
    Sources
    • Expert Review Green
    • Expert list
    Phenotypes
    • Weill-Marchesani syndrome 1, recessive, MIM# 277600

    Green ADAMTS10 in Mendeliome


    Version 1.1891

    		review BIALLELIC, autosomal or pseudoautosomal
    Sources
    • Expert Review Green
    • Expert list
    • Victorian Clinical Genetics Services
    Phenotypes
    • Weill-Marchesani syndrome 1, recessive, MIM#277600

    Green ADAMTS10 in Intellectual disability syndromic and non-syndromic


    Level 2: Neurology and neurodevelopmental disorders
    Version 0.6063

    		review BIALLELIC, autosomal or pseudoautosomal
    Sources
    • Expert Review Green
    • Genetic Health Queensland
    Phenotypes
    • Weill-Marchesani syndrome 1, recessive, MIM#277600

    Green ADAMTS10 in Skeletal dysplasia

    Level 3: Skeletal dysplasias
    Level 2: Skeletal disorders
    Version 0.285

    		review BIALLELIC, autosomal or pseudoautosomal
    Sources
    • Expert Review Green
    • NHS GMS
    • Expert list
    • Victorian Clinical Genetics Services
    Phenotypes
    • Weill-Marchesani syndrome 1, recessive, 277600

    Green ADAMTS10 in Hand and foot malformations


    Level 2: Dysmorphic and congenital abnormality syndromes
    Version 0.74

    Component of the following Super Panels:

  • Limb and Digital Malformations SuperPanel

    		•  review BIALLELIC, autosomal or pseudoautosomal
    Sources
    • Expert list
    • Expert Review Green
    • Expert Review Green
    • Expert list
    • Victorian Clinical Genetics Services
    • Expert Review Green
    Phenotypes
    • Weill-Marchesani syndrome 1, recessive, 277600

    Green ADAMTS10 in Fetal anomalies


    Version 1.255

    		review BIALLELIC, autosomal or pseudoautosomal
    Sources
    • Expert Review Green
    • Genomics England PanelApp
    • Genetic Health Queensland
    Phenotypes
    • Weill-Marchesani syndrome 1, recessive, MIM#277600