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| Defects of innate immunity v0.134 | MAP1LC3B2 | Zornitza Stark Marked gene: MAP1LC3B2 as ready | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Defects of innate immunity v0.134 | MAP1LC3B2 | Zornitza Stark Gene: map1lc3b2 has been classified as Red List (Low Evidence). | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Defects of innate immunity v0.134 | MAP1LC3B2 | Zornitza Stark Phenotypes for gene: MAP1LC3B2 were changed from Mollaret’s meningitis (recurrent lymphocytic meningitis) due to HSV2 to Hereditary susceptibility to infection, MONDO:0015979, MAP1LC3B2 -related; Mollaret’s meningitis (recurrent lymphocytic meningitis) due to HSV2 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Defects of innate immunity v0.133 | MAP1LC3B2 | Zornitza Stark Classified gene: MAP1LC3B2 as Red List (low evidence) | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Defects of innate immunity v0.133 | MAP1LC3B2 | Zornitza Stark Gene: map1lc3b2 has been classified as Red List (Low Evidence). | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Defects of innate immunity v0.132 | MAP1LC3B2 |
Sangavi Sivagnanasundram gene: MAP1LC3B2 was added gene: MAP1LC3B2 was added to Defects of innate immunity. Sources: Other Mode of inheritance for gene: MAP1LC3B2 was set to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted Publications for gene: MAP1LC3B2 were set to 35748970; 33310865 Phenotypes for gene: MAP1LC3B2 were set to Mollaret’s meningitis (recurrent lymphocytic meningitis) due to HSV2 Review for gene: MAP1LC3B2 was set to RED Added comment: Reviewed from PMID: 35748970 No published gene-disease association as of yet. Affects CNS (resident cells and fibroblasts) Impaired autophagy induction after HSV2 infection - increased viral replication and apoptosis of patient fibroblasts. PMID: 33310865 one affected individual with heterozygous mutation in MAP1LC3B2 (p.L109M) Sources: Other |
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