| Date | Panel | Item | Activity | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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| Motor Neurone Disease v0.187 | LGALSL | Bryony Thompson Marked gene: LGALSL as ready | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Motor Neurone Disease v0.187 | LGALSL | Bryony Thompson Gene: lgalsl has been classified as Amber List (Moderate Evidence). | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Motor Neurone Disease v0.187 | LGALSL | Bryony Thompson Classified gene: LGALSL as Amber List (moderate evidence) | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Motor Neurone Disease v0.187 | LGALSL | Bryony Thompson Gene: lgalsl has been classified as Amber List (Moderate Evidence). | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Motor Neurone Disease v0.186 | LGALSL |
Bryony Thompson gene: LGALSL was added gene: LGALSL was added to Motor Neurone Disease. Sources: ClinGen Mode of inheritance for gene: LGALSL was set to Unknown Publications for gene: LGALSL were set to 30940688 Phenotypes for gene: LGALSL were set to amyotrophic lateral sclerosis MONDO:0004976 Review for gene: LGALSL was set to AMBER Added comment: Limited gene-disease validity assessment by ClinGen ALS spectrum disorder GCEP - 14/02/2023. Significant enrichment in a cohort of 3,239 ALS cases compared to 11,808 controls - OR = 14.63; P = 2.29e-6. Sources: ClinGen |
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