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Systemic Autoinflammatory Disease_Periodic Fever v0.126 LACC1 Bryony Thompson Marked gene: LACC1 as ready
Systemic Autoinflammatory Disease_Periodic Fever v0.126 LACC1 Bryony Thompson Gene: lacc1 has been classified as Green List (High Evidence).
Systemic Autoinflammatory Disease_Periodic Fever v0.126 LACC1 Bryony Thompson Classified gene: LACC1 as Green List (high evidence)
Systemic Autoinflammatory Disease_Periodic Fever v0.126 LACC1 Bryony Thompson Gene: lacc1 has been classified as Green List (High Evidence).
Systemic Autoinflammatory Disease_Periodic Fever v0.125 LACC1 Bryony Thompson gene: LACC1 was added
gene: LACC1 was added to Systemic Autoinflammatory Disease_Periodic Fever. Sources: Literature
Mode of inheritance for gene: LACC1 was set to BIALLELIC, autosomal or pseudoautosomal
Publications for gene: LACC1 were set to 25220867; 27881174; 30872671; 33718577
Phenotypes for gene: LACC1 were set to Juvenile arthritis MIM#618795
Review for gene: LACC1 was set to GREEN
Added comment: At least 43 cases with biallelic variants (7 different variants) from 17 mainly consanguineous families reported. At least 10 of the families had systemic disease, which all demonstrated increased inflammatory markers.
Sources: Literature