| Date | Panel | Item | Activity | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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| Vascular Malformations_Germline v0.93 | KRAS | Zornitza Stark Marked gene: KRAS as ready | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Vascular Malformations_Germline v0.93 | KRAS | Zornitza Stark Gene: kras has been classified as Red List (Low Evidence). | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Vascular Malformations_Germline v0.22 | KRAS | Bryony Thompson Classified gene: KRAS as Red List (low evidence) | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Vascular Malformations_Germline v0.22 | KRAS | Bryony Thompson Added comment: Comment on list classification: Somatic activating mutations are the cause of vascular malformations in this gene, thus it is not suitable to include on a germline testing panel. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Vascular Malformations_Germline v0.22 | KRAS | Bryony Thompson Gene: kras has been classified as Red List (Low Evidence). | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Vascular Malformations_Germline v0.21 | KRAS |
Bryony Thompson gene: KRAS was added gene: KRAS was added to Inherited Vascular Malformations. Sources: Expert list somatic tags were added to gene: KRAS. Mode of inheritance for gene: KRAS was set to Other Publications for gene: KRAS were set to 30677207; 30544177; 31160609 Phenotypes for gene: KRAS were set to Arteriovenous malformation of the brain, somatic 108010; Vascular malformation Mode of pathogenicity for gene: KRAS was set to Other Review for gene: KRAS was set to GREEN Added comment: Somatic activating mutations in this gene cause sporadic vascular malformations, particularly CNS AVMs. Germline mutations cause RASopathies. Sources: Expert list |
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