| Date | Panel | Item | Activity | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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| Vascular Malformations_Germline v0.93 | GNA14 | Zornitza Stark Marked gene: GNA14 as ready | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Vascular Malformations_Germline v0.93 | GNA14 | Zornitza Stark Gene: gna14 has been classified as Red List (Low Evidence). | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Vascular Malformations_Germline v0.15 | GNA14 | Bryony Thompson Classified gene: GNA14 as Red List (low evidence) | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Vascular Malformations_Germline v0.15 | GNA14 | Bryony Thompson Added comment: Comment on list classification: Somatic activating mutations have only been reported to cause vascular malformations. This gene is not really suitable for a germline testing panel. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Vascular Malformations_Germline v0.15 | GNA14 | Bryony Thompson Gene: gna14 has been classified as Red List (Low Evidence). | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Vascular Malformations_Germline v0.14 | GNA14 |
Bryony Thompson gene: GNA14 was added gene: GNA14 was added to Vascular Malformations_RMH. Sources: Expert list somatic tags were added to gene: GNA14. Mode of inheritance for gene: GNA14 was set to Other Publications for gene: GNA14 were set to 31423605; 31707589; 27476652 Phenotypes for gene: GNA14 were set to Tufted angioma; Anastomosing hemangioma; vascular tumours Mode of pathogenicity for gene: GNA14 was set to Loss-of-function variants (as defined in pop up message) DO NOT cause this phenotype - please provide details in the comments Review for gene: GNA14 was set to GREEN Added comment: Somatic activating mutations cause sporadic and congenital vascular tumours. Sources: Expert list |
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