| Date | Panel | Item | Activity | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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| Early-onset Parkinson disease v0.240 | GIGYF2 | Bryony Thompson Publications for gene: GIGYF2 were set to 18358451; 33239198; 25279164; 20060621; 19250854; 26152800; 19449032 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Early-onset Parkinson disease v0.239 | GIGYF2 | Bryony Thompson Publications for gene: GIGYF2 were set to PMID: 18358451, 19449032 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Early-onset Parkinson disease v0.238 | GIGYF2 | Bryony Thompson Classified gene: GIGYF2 as Red List (low evidence) | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Early-onset Parkinson disease v0.238 | GIGYF2 | Bryony Thompson Gene: gigyf2 has been classified as Red List (Low Evidence). | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Early-onset Parkinson disease v0.237 | GIGYF2 | Bryony Thompson reviewed gene: GIGYF2: Rating: RED; Mode of pathogenicity: None; Publications: 18358451, 33239198, 25279164, 20060621, 19250854, 26152800; Phenotypes: {Parkinson disease 11} , OMIM # 607688; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Early-onset Parkinson disease v0.133 | GIGYF2 | Zornitza Stark Marked gene: GIGYF2 as ready | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Early-onset Parkinson disease v0.133 | GIGYF2 | Zornitza Stark Gene: gigyf2 has been classified as Amber List (Moderate Evidence). | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Early-onset Parkinson disease v0.133 | GIGYF2 | Chirag Patel Classified gene: GIGYF2 as Amber List (moderate evidence) | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Early-onset Parkinson disease v0.133 | GIGYF2 | Chirag Patel Gene: gigyf2 has been classified as Amber List (Moderate Evidence). | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Early-onset Parkinson disease v0.132 | GIGYF2 |
Chirag Patel gene: GIGYF2 was added gene: GIGYF2 was added to Early-onset Parkinson disease. Sources: Literature Mode of inheritance for gene: GIGYF2 was set to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted Publications for gene: GIGYF2 were set to PMID: 18358451, 19449032 Phenotypes for gene: GIGYF2 were set to {Parkinson disease 11} , OMIM # 607688 Review for gene: GIGYF2 was set to AMBER Added comment: In affected members of 12 unrelated Italian or French families with Parkinson disease-11 (PARK11; 607688), Lautier et al. (2008) identified 7 different heterozygous mutations in the GIGYF2 gene. Tan et al. (2009) identified 4 different heterozygous mutations in the GIGYF2 gene in 7 (1.6%) of 450 patients with Parkinson disease from Taiwan and Singapore. The mutations were not identified in 400 controls. Reduced penetrance seen in the families reported by both groups. No replication since. Sources: Literature |
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