| Date | Panel | Item | Activity | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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| Eye Anterior Segment Abnormalities v0.4 | FOXC2 | Zornitza Stark Marked gene: FOXC2 as ready | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Eye Anterior Segment Abnormalities v0.4 | FOXC2 | Zornitza Stark Gene: foxc2 has been classified as Green List (High Evidence). | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Eye Anterior Segment Abnormalities v0.4 | FOXC2 | Zornitza Stark Classified gene: FOXC2 as Green List (high evidence) | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Eye Anterior Segment Abnormalities v0.4 | FOXC2 | Zornitza Stark Gene: foxc2 has been classified as Green List (High Evidence). | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Eye Anterior Segment Abnormalities v0.0 | FOXC2 |
Chris Richmond gene: FOXC2 was added gene: FOXC2 was added to Eye Anterior Segment Abnormalities_VCGS. Sources: Literature Mode of inheritance for gene: FOXC2 was set to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted Publications for gene: FOXC2 were set to 12766066; 21730847 Phenotypes for gene: FOXC2 were set to Lymphedema-distichiasis syndrome 153400 Penetrance for gene: FOXC2 were set to unknown Review for gene: FOXC2 was set to GREEN Added comment: Ocular examination of patients with lymphedema-distichiasis syndrome and mutations in FOXC2, another member of the forkhead family, identified mild ASD, including partial iris hypoplasia, corectopia, reduced corneal diameter, and localized corneal opacification, in those with mutations within the forkhead domain (PMID: 21730847). No subsequent studies have investigated the role of FOXC2 in anterior segment dysgenesis. Sources: Literature |
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